OMSV enables accurate and comprehensive identification of large structural variations from nanochannel-based single-molecule optical maps

We present a new method, OMSV, for accurately and comprehensively identifying structural variations (SVs) from optical maps. OMSV detects both homozygous and heterozygous SVs, SVs of various types and sizes, and SVs with or without creating or destroying restriction sites. We show that OMSV has high...

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Detaylı Bibliyografya
Yayımlandı:Genome Biol
Asıl Yazarlar: Li, Le, Leung, Alden King-Yung, Kwok, Tsz-Piu, Lai, Yvonne Y. Y., Pang, Iris K., Chung, Grace Tin-Yun, Mak, Angel C. Y., Poon, Annie, Chu, Catherine, Li, Menglu, Wu, Jacob J. K., Lam, Ernest T., Cao, Han, Lin, Chin, Sibert, Justin, Yiu, Siu-Ming, Xiao, Ming, Lo, Kwok-Wai, Kwok, Pui-Yan, Chan, Ting-Fung, Yip, Kevin Y.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2017
Konular:
Method
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709945/
https://ncbi.nlm.nih.gov/pubmed/29195502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1356-2
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