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OMSV enables accurate and comprehensive identification of large structural variations from nanochannel-based single-molecule optical maps

We present a new method, OMSV, for accurately and comprehensively identifying structural variations (SVs) from optical maps. OMSV detects both homozygous and heterozygous SVs, SVs of various types and sizes, and SVs with or without creating or destroying restriction sites. We show that OMSV has high...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Li, Le, Leung, Alden King-Yung, Kwok, Tsz-Piu, Lai, Yvonne Y. Y., Pang, Iris K., Chung, Grace Tin-Yun, Mak, Angel C. Y., Poon, Annie, Chu, Catherine, Li, Menglu, Wu, Jacob J. K., Lam, Ernest T., Cao, Han, Lin, Chin, Sibert, Justin, Yiu, Siu-Ming, Xiao, Ming, Lo, Kwok-Wai, Kwok, Pui-Yan, Chan, Ting-Fung, Yip, Kevin Y.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709945/
https://ncbi.nlm.nih.gov/pubmed/29195502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1356-2
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