Comparison of quantification algorithms for circulating cell-free DNA methylation biomarkers in blood plasma from cancer patients

BACKGROUND: SHOX2 and SEPT9 methylation in circulating cell-free DNA (ccfDNA) in blood are established powerful and clinically valuable biomarkers for diagnosis, staging, prognosis, and monitoring of cancer patients. The aim of the present study was to evaluate different quantification algorithms (r...

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Veröffentlicht in:Clin Epigenetics
Hauptverfasser: de Vos, Luka, Gevensleben, Heidrun, Schröck, Andreas, Franzen, Alina, Kristiansen, Glen, Bootz, Friedrich, Dietrich, Dimo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Methodology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709918/
https://ncbi.nlm.nih.gov/pubmed/29213339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0425-4
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