SOX9 predicts progression toward cirrhosis in patients while its loss protects against liver fibrosis

Fibrosis and organ failure is a common endpoint for many chronic liver diseases. Much is known about the upstream inflammatory mechanisms provoking fibrosis and downstream potential for tissue remodeling. However, less is known about the transcriptional regulation in vivo governing fibrotic matrix d...

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Udgivet i:EMBO Mol Med
Main Authors: Athwal, Varinder S, Pritchett, James, Llewellyn, Jessica, Martin, Katherine, Camacho, Elizabeth, Raza, Sayyid MA, Phythian‐Adams, Alexander, Birchall, Lindsay J, Mullan, Aoibheann F, Su, Kim, Pearmain, Laurence, Dolman, Grace, Zaitoun, Abed M, Friedman, Scott L, MacDonald, Andrew, Irving, William L, Guha, Indra N, Hanley, Neil A, Piper Hanley, Karen
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709769/
https://ncbi.nlm.nih.gov/pubmed/29109128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201707860
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