Mycobacteria exploit nitric oxide‐induced transformation of macrophages into permissive giant cells

Immunity to mycobacteria involves the formation of granulomas, characterized by a unique macrophage (MΦ) species, so‐called multinucleated giant cells (MGC). It remains unresolved whether MGC are beneficial to the host, that is, by prevention of bacterial spread, or whether they promote mycobacteria...

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Vydáno v:EMBO Rep
Hlavní autoři: Gharun, Kourosh, Senges, Julia, Seidl, Maximilian, Lösslein, Anne, Kolter, Julia, Lohrmann, Florens, Fliegauf, Manfred, Elgizouli, Magdeldin, Vavra, Martina, Schachtrup, Kristina, Illert, Anna L, Gilleron, Martine, Kirschning, Carsten J, Triantafyllopoulou, Antigoni, Henneke, Philipp
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709734/
https://ncbi.nlm.nih.gov/pubmed/29097394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744121
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