Afatinib Therapy for Brain Metastases Aggravated by a Reduction in the Dose of Erlotinib Due to the Development of Hepatotoxicity

We report an 80-year-old woman with EGFR-mutant lung adenocarcinoma with multiple brain metastases (BMs). All lesions including BM showed a successful resolution after initiating daily 150 mg erlotinib. However, a grade 2 bilirubin-increase developed, and it was necessary to reduce the dose of erlot...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Intern Med
Main Authors: Yamanaka, Yumie, Sekine, Akimasa, Kato, Terufumi, Yamakawa, Hideaki, Ikeda, Satoshi, Baba, Tomohisa, Iwasawa, Tae, Okudela, Koji, Ogura, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: The Japanese Society of Internal Medicine 2017
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709634/
https://ncbi.nlm.nih.gov/pubmed/28943548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2169/internalmedicine.8638-16
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados