Low body surface area predicts hepatotoxicity of nintedanib in patients with idiopathic pulmonary fibrosis

After the commercialization of nintedanib in Japan, a high incidence of hepatotoxicity resulting in treatment interruption was noted in idiopathic pulmonary fibrosis (IPF) patients treated with nintedanib in our hospital. This study aimed to clarify the risk factors for hepatotoxicity of nintedanib....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ikeda, Satoshi, Sekine, Akimasa, Baba, Tomohisa, Yamanaka, Yumie, Sadoyama, Shinko, Yamakawa, Hideaki, Oda, Tsuneyuki, Okuda, Ryo, Kitamura, Hideya, Okudela, Koji, Iwasawa, Tae, Ohashi, Kenichi, Takemura, Tamiko, Ogura, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589740/
https://ncbi.nlm.nih.gov/pubmed/28883482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11321-x
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