Low body surface area predicts hepatotoxicity of nintedanib in patients with idiopathic pulmonary fibrosis

After the commercialization of nintedanib in Japan, a high incidence of hepatotoxicity resulting in treatment interruption was noted in idiopathic pulmonary fibrosis (IPF) patients treated with nintedanib in our hospital. This study aimed to clarify the risk factors for hepatotoxicity of nintedanib....

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Vydáno v:Sci Rep
Hlavní autoři: Ikeda, Satoshi, Sekine, Akimasa, Baba, Tomohisa, Yamanaka, Yumie, Sadoyama, Shinko, Yamakawa, Hideaki, Oda, Tsuneyuki, Okuda, Ryo, Kitamura, Hideya, Okudela, Koji, Iwasawa, Tae, Ohashi, Kenichi, Takemura, Tamiko, Ogura, Takashi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589740/
https://ncbi.nlm.nih.gov/pubmed/28883482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11321-x
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