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Induction of a novel isoform of the lncRNA HOTAIR in Claudin‐low breast cancer cells attached to extracellular matrix

Elevated overexpression of the lncRNA HOTAIR mediates invasion and metastasis in breast cancer. In an apparent paradox, we observed low expression of HOTAIR in the invasive Claudin‐low MDA‐MB‐231 and Hs578T cells in two‐dimensional culture (2D). However, HOTAIR expression exhibited robust induction...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Li, Miao, Li, Xi, Zhuang, Yan, Flemington, Erik K., Lin, Zhen, Shan, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709615/
https://ncbi.nlm.nih.gov/pubmed/28846832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12133
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