In Vitro Approach To Identify Key Amino Acids in Low Susceptibility of Rabbit Prion Protein to Misfolding

Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a group of rare progressive neurodegenerative disorders caused by an abnormally folded prion protein (PrP(Sc)). This is capable of transforming the normal cellular prion protein (PrP(C)) into new infectious PrP(Sc). Interspecie...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Virol
Prif Awduron: Eraña, Hasier, Fernández-Borges, Natalia, Elezgarai, Saioa R., Harrathi, Chafik, Charco, Jorge M., Chianini, Francesca, Dagleish, Mark P., Ortega, Gabriel, Millet, Óscar, Castilla, Joaquín
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2017
Pynciau:
Prions
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709604/
https://ncbi.nlm.nih.gov/pubmed/28978705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01543-17
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