In Vitro Approach To Identify Key Amino Acids in Low Susceptibility of Rabbit Prion Protein to Misfolding

Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a group of rare progressive neurodegenerative disorders caused by an abnormally folded prion protein (PrP(Sc)). This is capable of transforming the normal cellular prion protein (PrP(C)) into new infectious PrP(Sc). Interspecie...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Eraña, Hasier, Fernández-Borges, Natalia, Elezgarai, Saioa R., Harrathi, Chafik, Charco, Jorge M., Chianini, Francesca, Dagleish, Mark P., Ortega, Gabriel, Millet, Óscar, Castilla, Joaquín
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Prions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709604/
https://ncbi.nlm.nih.gov/pubmed/28978705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01543-17
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