Coat Protein Mutations That Alter the Flux of Morphogenetic Intermediates through the ϕX174 Early Assembly Pathway

Two scaffolding proteins orchestrate ϕX174 morphogenesis. The internal scaffolding protein B mediates the formation of pentameric assembly intermediates, whereas the external scaffolding protein D organizes 12 of these intermediates into procapsids. Aromatic amino acid side chains mediate most coat-...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Blackburn, Brody J., Li, Shuaizhi, Roznowski, Aaron P., Perez, Alexis R., Villarreal, Rodrigo H., Johnson, Curtis J., Hardy, Margaret, Tuckerman, Edward C., Burch, April D., Fane, Bentley A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709602/
https://ncbi.nlm.nih.gov/pubmed/28978706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01384-17
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