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Conformational Switch-Defective ϕX174 Internal Scaffolding Proteins Kinetically Trap Assembly Intermediates before Procapsid Formation

Conformational switching is an overarching paradigm in which to describe scaffolding protein-mediated virus assembly. However, rapid morphogenesis with small assembly subunits hinders the isolation of early morphogenetic intermediates in most model systems. Consequently, conformational switches are...

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Detalhes bibliográficos
Main Authors: Gordon, Emile B., Knuff, Christopher J., Fane, Bentley A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446603/
https://ncbi.nlm.nih.gov/pubmed/22761377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01120-12
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