Human Cytomegalovirus Utilizes a Nontraditional Signal Transducer and Activator of Transcription 1 Activation Cascade via Signaling through Epidermal Growth Factor Receptor and Integrins To Efficiently Promote the Motility, Differentiation, and Polarization of Infected Monocytes

Human cytomegalovirus (HCMV) infects peripheral blood monocytes and triggers biological changes that promote viral dissemination and persistence. We have shown that HCMV induces a proinflammatory state in infected monocytes, resulting in enhanced monocyte motility and transendothelial migration, pro...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Collins-McMillen, Donna, Stevenson, Emily V., Kim, Jung Heon, Lee, Byeong-Jae, Cieply, Stephen J., Nogalski, Maciej T., Chan, Gary C., Frost, Robert W., Spohn, Caroline R., Yurochko, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709601/
https://ncbi.nlm.nih.gov/pubmed/29021395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00622-17
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