Human Cytomegalovirus Promotes Survival of Infected Monocytes via a Distinct Temporal Regulation of Cellular Bcl-2 Family Proteins

Monocytes play a key role in the hematogenous dissemination of human cytomegalovirus (HCMV) to target organ systems. To infect monocytes and reprogram them to deliver infectious virus, HCMV must overcome biological obstacles, including the short life span of monocytes and their antiviral proapoptoti...

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Publicado en:J Virol
Autores principales: Collins-McMillen, Donna, Kim, Jung Heon, Nogalski, Maciej T., Stevenson, Emily V., Chan, Gary C., Caskey, Joshua R., Cieply, Stephen J., Yurochko, Andrew D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810730/
https://ncbi.nlm.nih.gov/pubmed/26676786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01994-15
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