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T Cell-Macrophage Fusion Triggers Multinucleated Giant Cell Formation for HIV-1 Spreading

HIV-1-infected macrophages participate in virus dissemination and establishment of virus reservoirs in host tissues, but the mechanisms for virus cell-to-cell transfer to macrophages remain unknown. Here, we reveal the mechanisms for cell-to-cell transfer from infected T cells to macrophages and vir...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Bracq, Lucie, Xie, Maorong, Lambelé, Marie, Vu, Lan-Trang, Matz, Julie, Schmitt, Alain, Delon, Jérôme, Zhou, Paul, Randriamampita, Clotilde, Bouchet, Jérôme, Benichou, Serge
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709600/
https://ncbi.nlm.nih.gov/pubmed/28978713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01237-17
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