Computationally Optimized Broadly Reactive Hemagglutinin Elicits Hemagglutination Inhibition Antibodies against a Panel of H3N2 Influenza Virus Cocirculating Variants

Each influenza season, a set of wild-type viruses, representing one H1N1, one H3N2, and one to two influenza B isolates, are selected for inclusion in the annual seasonal influenza vaccine. In order to develop broadly reactive subtype-specific influenza vaccines, a methodology called computationally...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Wong, Terianne M., Allen, James D., Bebin-Blackwell, Anne-Gaelle, Carter, Donald M., Alefantis, Timothy, DiNapoli, Joshua, Kleanthous, Harold, Ross, Ted M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709590/
https://ncbi.nlm.nih.gov/pubmed/28978710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01581-17
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