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Estrogen attenuates AGTR1 expression to reduce pancreatic β-cell death from high glucose
Chronic exposure of pancreatic β-cells to high glucose levels results in β-cell dysfunction and death. These effects can be protected by estrogen. The local pancreatic renin-angiotensin system (RAS) has been shown as a novel pathological pathway of high-glucose-induced cell death. The effect of estr...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5709427/ https://ncbi.nlm.nih.gov/pubmed/29192236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15237-4 |
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