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Influence of the Novel ATP-Competitive Dual mTORC1/2 Inhibitor AZD2014 on Immune Cell Populations and Heart Allograft Rejection
BACKGROUND: Little is known about how new generation adenosine triphosphate (ATP)-competitive mechanistic target of rapamycin (mTOR) kinase inhibitors (TORKinibs) affect immunity and allograft rejection. METHODS: mTOR complex (C) 1 and 2 signaling in dendritic cells (DC) and T cells was analyzed by...
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發表在: | Transplantation |
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Main Authors: | , , , , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
2017
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5709200/ https://ncbi.nlm.nih.gov/pubmed/28885497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000001933 |
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