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Prevention and reversal of social stress-escalated cocaine self-administration in mice by intra-VTA CRFR1 antagonism
BACKGROUND: A history of brief intermittent social defeat stress can escalate cocaine self-administration and induce long-term adaptations in the mesolimbic dopamine system. Extra-hypothalamic corticotrophin releasing factor (CRF) has been shown to be closely associated with stress-induced escalatio...
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| Publicado en: | Psychopharmacology (Berl) |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5709170/ https://ncbi.nlm.nih.gov/pubmed/28698920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-017-4676-8 |
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