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CRF type 1 receptor antagonism in ventral tegmental area of adolescent rats during social defeat: Prevention of escalated cocaine self-administration in adulthood and behavioral adaptations during adolescence
BACKGROUND: Activation of corticotropin releasing factor type 1 receptors (CRF-R1) in the ventral tegmental area (VTA) represents a critical mechanism for social defeat to escalate cocaine self-administration in adult rats. OBJECTIVE: We determined the acute effect of a CRF-R1 antagonist (CP376395)...
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| Pubblicato in: | Psychopharmacology (Berl) |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4919183/ https://ncbi.nlm.nih.gov/pubmed/27251131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-016-4336-4 |
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