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Escalated cocaine “binges” in rats: enduring effects of social defeat stress or intra-VTA CRF

RATIONALE: Exposure to intermittent social defeat stress elicits CRF release into the VTA, and induces long-term modulation of mesocorticolimbic dopamine activity in rats. These adaptations are associated with an intense cocaine-taking phenotype, which is prevented by CRF receptor antagonists. OBJEC...

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Détails bibliographiques
Publié dans:Psychopharmacology (Berl)
Auteurs principaux: Leonard, Michael Z., DeBold, Joseph F., Miczek, Klaus A.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709163/
https://ncbi.nlm.nih.gov/pubmed/28725939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-017-4677-7
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