The kinesin spindle protein inhibitor filanesib enhances the activity of pomalidomide and dexamethasone in multiple myeloma

Kinesin spindle protein inhibition is known to be an effective therapeutic approach in several malignancies. Filanesib (ARRY-520), an inhibitor of this protein, has demonstrated activity in heavily pre-treated multiple myeloma patients. The aim of the work herein was to investigate the activity of f...

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Pubblicato in:Haematologica
Autori principali: Hernández-García, Susana, San-Segundo, Laura, González-Méndez, Lorena, Corchete, Luis A., Misiewicz-Krzeminska, Irena, Martín-Sánchez, Montserrat, López-Iglesias, Ana-Alicia, Algarín, Esperanza Macarena, Mogollón, Pedro, Díaz-Tejedor, Andrea, Paíno, Teresa, Tunquist, Brian, Mateos, María-Victoria, Gutiérrez, Norma C, Díaz-Rodriguez, Elena, Garayoa, Mercedes, Ocio, Enrique M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709111/
https://ncbi.nlm.nih.gov/pubmed/28860344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2017.168666
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