Protein Translation Inhibition is Involved in the Activity of the Pan-PIM Kinase Inhibitor PIM447 in Combination with Pomalidomide-Dexamethasone in Multiple Myeloma

SIMPLE SUMMARY: The identification of new pharmacological combinations with synergistic effect in multiple myeloma is highly relevant since this is, for the moment, an incurable disease. The high expression of Proviral Insertion site for Moloney murine leukemia virus (PIM) kinases, especially PIM2,...

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Опубликовано в: :Cancers (Basel)
Главные авторы: Paíno, Teresa, González-Méndez, Lorena, San-Segundo, Laura, Corchete, Luis A., Hernández-García, Susana, Díaz-Tejedor, Andrea, Algarín, Esperanza M., Mogollón, Pedro, Martín-Sánchez, Montserrat, Gutiérrez, Norma C., Mateos, María-Victoria, Garayoa, Mercedes, Ocio, Enrique M.
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7598606/
https://ncbi.nlm.nih.gov/pubmed/32987735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12102743
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