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Role of SHP2 in Hematopoiesis and Leukemogenesis
PURPOSE OF REVIEW: SH2 domain-containing tyrosine phosphatase 2 (SHP2), encoded by PTPN11 plays an important role in regulating signaling from cell surface receptor tyrosine kinases during normal development as well as oncogenesis. Herein we review recently discovered roles of SHP2 in normal and abe...
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| Publicado no: | Curr Opin Hematol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5709049/ https://ncbi.nlm.nih.gov/pubmed/28306669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000345 |
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