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Role of SHP2 in Hematopoiesis and Leukemogenesis
PURPOSE OF REVIEW: SH2 domain-containing tyrosine phosphatase 2 (SHP2), encoded by PTPN11 plays an important role in regulating signaling from cell surface receptor tyrosine kinases during normal development as well as oncogenesis. Herein we review recently discovered roles of SHP2 in normal and abe...
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| Publicat a: | Curr Opin Hematol |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5709049/ https://ncbi.nlm.nih.gov/pubmed/28306669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000345 |
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