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APOE allele frequencies in suspected non-amyloid pathophysiology (SNAP) and the prodromal stages of Alzheimer’s Disease

Biomarker definitions for preclinical Alzheimer’s disease (AD) have identified individuals with neurodegeneration (ND+) without β-amyloidosis (Aβ-) and labeled them with suspected non-AD pathophysiology (SNAP). We evaluated Apolipoprotein E (APOE) ε2 and ε4 allele frequencies across biomarker defini...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hohman, Timothy J., Dumitrescu, Logan, Oksol, Amy, Wagener, Madison, Gifford, Katherine A., Jefferson, Angela L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5708777/
https://ncbi.nlm.nih.gov/pubmed/29190651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188501
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