Encryption of agonistic motifs for TLR4 into artificial antigens augmented the maturation of antigen-presenting cells

Adjuvants are indispensable for achieving a sufficient immune response from vaccinations. From a functional viewpoint, adjuvants are classified into two categories: “physical adjuvants” increase the efficacy of antigen presentation by antigen-presenting cells (APC) and “signal adjuvants” induce the...

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Publicado no:PLoS One
Main Authors: Ito, Masaki, Hayashi, Kazumi, Minamisawa, Tamiko, Homma, Sadamu, Koido, Shigeo, Shiba, Kiyotaka
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5708714/
https://ncbi.nlm.nih.gov/pubmed/29190754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188934
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https://ncbi.nlm.nih.gov/pmc/articles/PMC5708714/
https://ncbi.nlm.nih.gov/pubmed/29190754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188934