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Role of cis-trans proline isomerization in the function of pathogenic enterobacterial Periplasmic Binding Proteins

Periplasmic Binding Proteins (PBPs) trap nutrients for their internalization into bacteria by ABC transporters. Ligand binding triggers PBP closure by bringing its two domains together like a Venus flytrap. The atomic determinants that control PBP opening and closure for nutrient capture and release...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cortes-Hernandez, Paulina, Domínguez-Ramírez, Lenin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5708682/
https://ncbi.nlm.nih.gov/pubmed/29190818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188935
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