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Computational and NMR spectroscopy insights into the conformation of cyclic di-nucleotides
Cyclic di-nucleotides (CDNs) are second messengers in bacteria and metazoan that are as such controlling important biological processes. Here the conformational space of CDNs was explored systematically by a combination of extensive conformational search and DFT calculations as well as NMR methods....
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5707406/ https://ncbi.nlm.nih.gov/pubmed/29185472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16794-4 |
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