O-GlcNAcylation is required for B cell homeostasis and antibody responses

O-linked N-acetylglucosamine (O-GlcNAc) transferase (Ogt) catalyzes O-GlcNAc modification. O-GlcNAcylation is increased after cross-linking of the B-cell receptor (BCR), but the physiological function of this reaction is unknown. Here we show that lack of Ogt in B-cell development not only causes se...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Wu, Jung-Lin, Chiang, Ming-Feng, Hsu, Pan-Hung, Tsai, Dong-Yen, Hung, Kuo-Hsuan, Wang, Ying-Hsiu, Angata, Takashi, Lin, Kuo-I
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707376/
https://ncbi.nlm.nih.gov/pubmed/29187734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01677-z
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars