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IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression

IL-27 and IL-35 are heterodimeric cytokines, members of the IL-12 family and considered to have immunomodulatory properties. Their role during neuroinflammation had been investigated using mutant mice devoid of either one of their subunits or lacking components of their receptors, yielding conflicti...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Casella, Giacomo, Finardi, Annamaria, Descamps, Hélène, Colombo, Federico, Maiorino, Chiara, Ruffini, Francesca, Patrone, Marco, Degano, Massimo, Martino, Gianvito, Muzio, Luca, Becher, Burkhard, Furlan, Roberto
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707351/
https://ncbi.nlm.nih.gov/pubmed/29185463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16702-w
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