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Activation of Discs large by aPKC aligns the mitotic spindle to the polarity axis during asymmetric cell division

Asymmetric division generates cellular diversity by producing daughter cells with different fates. In animals, the mitotic spindle aligns with Par complex polarized fate determinants, ensuring that fate determinant cortical domains are bisected by the cleavage furrow. Here, we investigate the mechan...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Golub, Ognjen, Wee, Brett, Newman, Rhonda A, Paterson, Nicole M, Prehoda, Kenneth E
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706957/
https://ncbi.nlm.nih.gov/pubmed/29185419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32137
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