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Nrf2 induces cisplatin resistance via suppressing the iron export related gene SLC40A1 in ovarian cancer cells

Induction of Nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2) has been demonstrated to be involved in cisplatin resistance in ovarian cancer. Solute carrier family 40 member 1 (SLC40A1) is an iron exporter, which possesses many putative Nrf2 binding sites. Here we hypothesize that it may b...

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Vydáno v:Oncotarget
Hlavní autoři: Wu, Jianfa, Bao, Lingjie, Zhang, Zhenbo, Yi, Xiaofang
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706814/
https://ncbi.nlm.nih.gov/pubmed/29212168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19548
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