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PRPF8 is important for BRCA1-mediated homologous recombination
Disruption of RNA splicing causes genome instability, which could contribute to cancer etiology. Furthermore, RNA splicing is an emerging anti-cancer target. Thus, we have evaluated the influence of the spliceosome factor PRPF8 and the splicing inhibitor Pladienolide B (PlaB) on homologous recombina...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5706798/ https://ncbi.nlm.nih.gov/pubmed/29212152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21555 |
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