Synthetic “smart gel” provides glucose-responsive insulin delivery in diabetic mice

Although previous studies have attempted to create “electronics-free” insulin delivery systems using glucose oxidase and sugar-binding lectins as a glucose-sensing mechanism, no successful clinical translation has hitherto been made. These protein-based materials are intolerant of long-term use and...

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Bibliografiske detaljer
Udgivet i:Sci Adv
Main Authors: Matsumoto, Akira, Tanaka, Miyako, Matsumoto, Hiroko, Ochi, Kozue, Moro-oka, Yuki, Kuwata, Hirohito, Yamada, Hironori, Shirakawa, Ibuki, Miyazawa, Taiki, Ishii, Hitoshi, Kataoka, Kazunori, Ogawa, Yoshihiro, Miyahara, Yuji, Suganami, Takayoshi
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706739/
https://ncbi.nlm.nih.gov/pubmed/29202033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaq0723
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