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A Bayesian method for detecting pairwise associations in compositional data

Compositional data consist of vectors of proportions normalized to a constant sum from a basis of unobserved counts. The sum constraint makes inference on correlations between unconstrained features challenging due to the information loss from normalization. However, such correlations are of long-st...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Schwager, Emma, Mallick, Himel, Ventz, Steffen, Huttenhower, Curtis
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706738/
https://ncbi.nlm.nih.gov/pubmed/29140991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005852
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