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Parallel arrangements of positive feedback loops limit cell-to-cell variability in differentiation

Cellular differentiations are often regulated by bistable switches resulting from specific arrangements of multiple positive feedback loops (PFL) fused to one another. Although bistability generates digital responses at the cellular level, stochasticity in chemical reactions causes population hetero...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Dey, Anupam, Barik, Debashis
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706692/
https://ncbi.nlm.nih.gov/pubmed/29186174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188623
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