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Controlling Regioselectivity in the Enantioselective N-Alkylation of Indole Analogs Catalyzed by Dinuclear Zinc-ProPhenol
The enantioselective N-alkylation of indole and its derivatives with aldimines is efficiently catalyzed by a zinc-ProPhenol dinuclear complex under mild conditions to afford N-alkylated indole derivatives in good yield (up to 86%) and excellent enantiomeric ratio (up to 99.5: 0.5 e.r.). This protoco...
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| Pubblicato in: | Angew Chem Int Ed Engl |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5706662/ https://ncbi.nlm.nih.gov/pubmed/28654735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201705315 |
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