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Cardiovascular effects of exogenous adrenomedullin and CGRP in Ramp and Calcrl deficient mice

Adrenomedullin (AM) and calcitonin gene-related peptide (CGRP) are potent vasodilator peptides and serve as ligands for the G-protein coupled receptor (GPCR) calcitonin receptor-like receptor (CLR/Calcrl). Three GPCR accessory proteins called receptor activity-modifying proteins (RAMPs) modify the l...

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Bibliographic Details
Published in:Peptides
Main Authors: Pawlak, J.B., Wetzel-Strong, S.E., Dunn, M.K., Caron, K.M.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706544/
https://ncbi.nlm.nih.gov/pubmed/27940069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2016.12.002
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