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Resolution Enhancement in Solid-State NMR of Oriented Membrane Proteins by Anisotropic Differential Linebroadening

We demonstrate that a significant improvement in the spectral resolution may be achieved in solid-state NMR experiments of proteins in inhomogeneously disordered oriented lipid bilayers. Using (1)H homonuclear decoupling instead of standard (1)H heteronuclear decoupling, the (15)N linewidths may be...

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Publicat a:J Am Chem Soc
Autors principals: Vosegaard, Thomas, Bertelsen, Kresten, Pedersen, Jan M., Thøgersen, Lea, Schiøtt, Birgit, Tajkhorshid, Emad, Skrydstrup, Troels, Nielsen, Niels Chr.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706113/
https://ncbi.nlm.nih.gov/pubmed/18341279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja8000612
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