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Pardaxin Permeabilizes Vesicles More Efficiently by Pore Formation than by Disruption

Pardaxin is a 33-amino-acid neurotoxin from the Red Sea Moses sole Pardachirus marmoratus, whose mode of action shows remarkable sensitivity to lipid chain length and charge, although the effect of pH is unclear. Here we combine optical spectroscopy and dye release experiments with laser scanning co...

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Détails bibliographiques
Auteurs principaux: Vad, Brian S., Bertelsen, Kresten, Johansen, Charlotte Hau, Pedersen, Jan Mondrup, Skrydstrup, Troels, Nielsen, Niels Chr., Otzen, Daniel E.
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820650/
https://ncbi.nlm.nih.gov/pubmed/20159154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.08.063
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