Modification of proteolytic activity matrix analysis (PrAMA) to measure ADAM10 and ADAM17 sheddase activities in cell and tissue lysates

Increases in expression of ADAM10 and ADAM17 genes and proteins have been evaluated, but not validated as cancer biomarkers. Specific enzyme activities better reflect enzyme cellular functions, and might be better biomarkers than enzyme genes or proteins. However, no high throughput assay is availab...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Yoneyama, Toshie, Gorry, Michael, Miller, Miles A, Gaither-Davis, Autumn, Lin, Yan, Moss, Marcia L., Griffith, Linda G., Lauffenburger, Douglas A., Stabile, Laura P., Herman, James G., Vujanovic, Nikola L.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705993/
https://ncbi.nlm.nih.gov/pubmed/29187866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.20779
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