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The Aromatic Head Group of Spider Toxin Polyamines Influences Toxicity to Cancer Cells

Spider venoms constitute incredibly diverse libraries of compounds, many of which are involved in prey capture and defence. Polyamines are often prevalent in the venom and target ionotropic glutamate receptors. Here we show that a novel spider polyamine, PA(366), containing a hydroxyphenyl-based str...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Wilson, David, Boyle, Glen M., McIntyre, Lachlan, Nolan, Matthew J., Parsons, Peter G., Smith, Jennifer J., Tribolet, Leon, Loukas, Alex, Liddell, Michael J., Rash, Lachlan D., Daly, Norelle L.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705961/
https://ncbi.nlm.nih.gov/pubmed/29077051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins9110346
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