Unbiased Quantitation of Alveolar Type II to Alveolar Type I Cell Transdifferentiation during Repair after Lung Injury in Mice

The alveolar epithelium consists of squamous alveolar type (AT) I and cuboidal ATII cells. ATI cells cover 95–98% of the alveolar surface, thereby playing a critical role in barrier integrity, and are extremely thin, thus permitting efficient gas exchange. During lung injury, ATI cells die, resultin...

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Vydáno v:Am J Respir Cell Mol Biol
Hlavní autoři: Jansing, Nicole L., McClendon, Jazalle, Henson, Peter M., Tuder, Rubin M., Hyde, Dallas M., Zemans, Rachel L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2017
Témata:
Major Technical Advances
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705906/
https://ncbi.nlm.nih.gov/pubmed/28586241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0037MA
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