Hypoxia-Inducible Factor 1α Signaling Promotes Repair of the Alveolar Epithelium after Acute Lung Injury

During the acute respiratory distress syndrome, epithelial cells, primarily alveolar type (AT) I cells, die and slough off, resulting in enhanced permeability. ATII cells proliferate and spread onto the denuded basement membrane to reseal the barrier. Repair of the alveolar epithelium is critical fo...

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Vydáno v:Am J Pathol
Hlavní autoři: McClendon, Jazalle, Jansing, Nicole L., Redente, Elizabeth F., Gandjeva, Aneta, Ito, Yoko, Colgan, Sean P., Ahmad, Aftab, Riches, David W.H., Chapman, Harold A., Mason, Robert J., Tuder, Rubin M., Zemans, Rachel L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2017
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530913/
https://ncbi.nlm.nih.gov/pubmed/28618253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.04.012
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