Ecto-ADP-ribosyltransferase ARTC2.1 functionally modulates FcγR1 and FcγR2B on murine microglia

Mammalian ecto-ADP-ribosyltransferases (ecto-ARTs or also ARTCs) catalyze the ADP-ribosylation of cell surface proteins using extracellular nicotinamide adenine dinucleotide (NAD(+)) as substrate. By this post-translational protein modification, ecto-ARTs modulate the function of various target prot...

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Udgivet i:Sci Rep
Main Authors: Rissiek, Björn, Menzel, Stephan, Leutert, Mario, Cordes, Maike, Behr, Sarah, Jank, Larissa, Ludewig, Peter, Gelderblom, Mathias, Rissiek, Anne, Adriouch, Sahil, Haag, Friedrich, Hottiger, Michael O., Koch-Nolte, Friedrich, Magnus, Tim
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705771/
https://ncbi.nlm.nih.gov/pubmed/29184112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16613-w
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