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Induced cortical tension restores functional junctions in adhesion-defective carcinoma cells

Normal epithelial cells are stably connected to each other via the apical junctional complex (AJC). AJCs, however, tend to be disrupted during tumor progression, and this process is implicated in cancer dissemination. Here, using colon carcinoma cells that fail to form AJCs, we investigated molecula...

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Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Ito, Shoko, Okuda, Satoru, Abe, Masako, Fujimoto, Mari, Onuki, Tetsuo, Nishimura, Tamako, Takeichi, Masatoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705652/
https://ncbi.nlm.nih.gov/pubmed/29184140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01945-y
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