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Induced cortical tension restores functional junctions in adhesion-defective carcinoma cells

Normal epithelial cells are stably connected to each other via the apical junctional complex (AJC). AJCs, however, tend to be disrupted during tumor progression, and this process is implicated in cancer dissemination. Here, using colon carcinoma cells that fail to form AJCs, we investigated molecula...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Ito, Shoko, Okuda, Satoru, Abe, Masako, Fujimoto, Mari, Onuki, Tetsuo, Nishimura, Tamako, Takeichi, Masatoshi
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705652/
https://ncbi.nlm.nih.gov/pubmed/29184140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01945-y
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