Platelet-Derived Growth Factor Regulates YAP Transcriptional Activity via Src Family Kinase Dependent Tyrosine Phosphorylation

The Hippo pathway effector YAP is implicated in the pathogenesis of cholangiocarcinoma (CCA). The Hippo pathway relies on signaling cross talk for its regulation. Given the importance of platelet derived growth factor receptor (PDGFR) signaling in CCA biology, our aim was to examine potential YAP re...

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Publié dans:J Cell Biochem
Auteurs principaux: Smoot, Rory L., Werneburg, Nathan W., Sugihara, Takaaki, Hernandez, Matthew C., Yang, Lin, Mehner, Christine, Graham, Rondell P., Bronk, Steven F., Truty, Mark J., Gores, Gregory J.
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705491/
https://ncbi.nlm.nih.gov/pubmed/28661054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.26246
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