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Structure-based release analysis of the JC virus agnoprotein regions: A role for the hydrophilic surface of the major alpha helix domain in release

Agnoprotein (Agno) is an important regulatory protein of JC virus (JCV), BK virus (BKV) and simian virus 40 (SV40) and these viruses are unable to replicate efficiently in the absence of this protein. Recent 3D–NMR structural data revealed that Agno contains two alpha-helices (a minor and a major) w...

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Pubblicato in:J Cell Physiol
Autori principali: Saribas, A. Sami, White, Martyn K., Safak, Mahmut
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705473/
https://ncbi.nlm.nih.gov/pubmed/28722139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.26106
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